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Sitagliptin
Clinical data
Trade namesJanuvia
AHFS/Drugs.comMonograph
MedlinePlusa606023
License dataEU  EMA:  by INN, US   FDA: Sitagliptin
Pregnancy categoryAU: B3 US: B (No risk in non-human studies)
Routes of administrationOral
ATC codeA10BH01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability87%
Protein binding38%
MetabolismHepatic (CYP3A4- and CYP2C8-mediated)
Elimination half-life8 to 14 h [1]
ExcretionRenal (80%) [1]

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