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Diclofenac (diclofenac, diclofenac) 100 mg, be sure to tell your doctor about all of the medications you take and any other medical conditions as your dose may need to be adjusted.

Diclofenac the recommended dose is 50 mg. When is co-administered with an alpha-blocker.

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Diclofenac
Clinical data
Trade namesCataflam, Voltaren, see trade names [1]
AHFS/Drugs.comMonograph
MedlinePlusa689002
Pregnancy categoryAU: C US: C (Risk not ruled out) in 1st and 2nd trimester, D in 3rd trimester,
Routes of administrationoral, rectal, intramuscular, intravenous (renal- and gallstones), topical
ATC codeD11AX18 ( WHO ) M01AB05 ( WHO ), M02AA15 ( WHO ), S01BC03 ( WHO )
Legal status
Legal statusAU: S2 (Pharmacy only) – S4, UK: POM (Prescription only) (P for topical formulation), ℞-only in most preparations/countries, limited OTC in some countries, manufacture and veterinary use is banned in India, Nepal, and Pakistan due to imminent extinction of local vultures
Pharmacokinetic data
Protein bindingMore than 99%
Metabolismhepatic, oxidative, primarily by CYP2C9, also by CYP2C8, CYP3A4, as well as conjugative by glucuronidation (UGT2B7) and sulfation; [2] no active metabolites exist
Elimination half-life1.2–2 hr (35% of the drug enters enterohepatic recirculation)
Excretion40% biliary 60% urine

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Use is contraindicated.

AU TGA pregnancy category: D US FDA pregnancy category: -Oral tablets: Pregnancy X -IM and SC injection: Not assigned Comments: -Evaluate the potential hazard to the fetus if this drug is used during pregnancy, or if pregnancy occurs while using this drug.

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